The objective of our study was to test the comparative efficiency of neem (Azadirachta indica) kernel oil, groundnut oil and a synthetic insecticide, K-Othrine, in protecting stocks of leguminous tree seeds against seed beetles under Sahelian conditions. The following insec/seed combinations were used as models : Caryedon acaciae/Acacia nilotica, C. longispinosus/A. raddiana and C. serratus/Tamarindus indica. Neem oil, when used at concentrations of 5 to 20 ml per kg of seeds, had pronounced adulticidal and ovicidal effects which were maintained for five months. No significant fall in seed viability was observed except in the case of C. acaciae/A. nilotica. Groundnut oil, when used at concentrations of 5 to 20 ml per kg of seeds, had pronounced adulticidal and ovicidal effects which were relatively shod-lived. A significant fall in seed viability was observed over five months. K-Othrine, when used at concentrations ranging from 25 to 100 mg per kg, had high adulticidal effects which were maintained for five months. However, K-Othrine was found to have no ovicide properties. No significant fall in seed viability was observed. This study concluded that it is possible to use neem oil, a product that can be obtained locally at low cost, to efficiently protect tree seed stocks in the Sahel.