Vasconcellea cundinamarconsis is one the best known and most promising mountain papayas. Reported here are spindle absence and the resulting abnormalitles, as chromosome missegregation, micronucler-dependent cylokinesis and cell death in one accession collected in the Andes of Ecuador. Spindle absence and cell death resulted in a high trequency of unviable meiotic products (83.48%). We propose the hypothesis of a detective spindle checkpoint leading to the absence of spindle microtubules in this accession of V. cundinamarcensis. However, this faulty checkpoint did not impede the progress and completion of meiosis, although in a non-conventional manner.