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Genetic characterization and antibiotic resistance of Campylobacter spp. isolated from poultry and humans in Senegal

Cardinale E., Rose V., Perrier Gros-Claude J.D., Tall F., Rivoal K., Mead G.C., Salvat G.. 2007. In : Camus Emmanuel (ed.), Cardinale Eric (ed.), Dalibard Christophe (ed.), Martinez Dominique (ed.), Renard Jean-François (ed.), Roger François (ed.). Does control of animal infectious risks offer a new international perspective ? : proceedings of the 12th International Conference of the Association of Institutions of Tropical Veterinary Medicine, Montpellier, France, 20-22 August 2007. Montpellier : CIRAD, p. 247-252. International Conference of the Association of Institutions of Tropical Veterinary Medicine. 12, 2007-08-20/2007-08-22, Montpellier (France).

The main objectives of this study were to investigate the diversity of Campylobacter genotypes circulating in Senegal and to determine the frequency of antibiotic resistance. Strains of C. jejuni isolated from poultry (n=99) and from patients (n=10) and C. coli isolated from poultry (n=72) were subtyped by pulsed-field gel electrophoresis (PFGE). The pulsotypes obtained revealed a significant genetic diversity in both species, but without any predominant pulsotypes. However, farm-specific clones were identified in the majority of poultry houses (76.5%). Human and poultry isolates of C. jejuni had common PFGE patterns. High quinolone-resistance rates were observed for C. jejuni (43.4%) and C. coli (48.6%) isolates obtained from poultry.

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