In this paper the results of laboratory tests of extracts of four plants, namely Mucuna pruriens (Fabaceae), Adenium obesum (Apocynaceae), Azadirachta indica (Meliaceae) and Calotropis procera (Asclepiadaceae) against the migratory locust (Locusta migratoria) are presented. The extracts were prepared using water or water/ethanol as solvents and screened for their locusticidal properties, both as contact and stomach poisons. Knockdown, mortality and time to death were considered as indicators for efficacy. The bio-tests have shown that Mucuna extracts act both as contact and stomach poisons. Up to 99% mortality was achieved by direct spraying of water or water/ethanol extracts of Mucuna at 50 g/l on the migratory locust, and similar percentage kill was also obtained when locusts were fed on wheat seedlings treated with Mucuna at 50 g/l (water/ethanol extract). Mucuna extracts, also appeared to act faster than neem extracts on locust. The study concluded that Mucuna has a potential as an effective natural product which can be used in different plant protection activities.