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Search for antifungal compounds from the wood of durable tropical trees

Rodrigues A.M.S., Theodoro P.N.E.T., Eparvier V., Basset C., Silva M.R.R., Beauchêne J., Espindola L.S., Stien D.. 2010. Journal of Natural Products, 73 (10) : p. 1706-1707.

Research on antifungal compounds from the durable wood from French Guiana Amazonian forest trees highlights the correlation between the activity of their extracts against wood-rotting fungi and human pathogens. The fractionation of an ethyl acetate extract of Sextonia rubra wood led to the isolation of rubrenolide (1) and rubrynolide (2). The potential of compounds 1 and 2 is described through the evaluation of their activity against 16 pathogenic fungi and their cytotoxicity toward NIH-3T3 mammalian fibroblast cells. (Résumé d'auteur)

Mots-clés : bois tropical; maladie de l'homme; maladie des plantes; fongicide; forêt tropicale humide; bois; extrait d'origine végétale; ocotea; guyane française; ocotea rubra

Thématique : Technologie des produits forestiers; Physiologie et biochimie végétales; Maladies des animaux

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