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Cirad

EPidemiology of Avian Influenza in Africa (EPIAAF) Survey : Final report. LoA PR 37212 between FAO and CIRAD

Waret A., Garba Maina A., Cristalli A., Nchare A., Gercona A.A.M., Ali A.M.M., Globig A., Haesler B., Staubach C., Hoereth-Boentgen D., Etter E., Miguel E., Cilloni F., Diesel G., Fournié G., Tiam H., Bangana I., Cappelle J., Soliman M.A., N'Goran Koffi J.N., Kranz P., Nisi R., Molia S., Boehle W.. 2009. Rome : FAO, 193 p..

The objective of the EPIAAF (Epidemiology of Avian Influenza in AFrica) survey was to better understand the epidemiology of HPAI in Africa by assessing risk factors linked to the introduction, diffusion and persistence of HPAI outbreak foci in seven infected countries (Burkina Faso, Cameroon, Egypt, Ivory Coast, Niger, Nigeria and Sudan). CIRAD was contracted by FAO through a LoA signed in November 2007 to conduct the survey which was implemented in collaboration with four European research institutes (FLI, IZSVe, RVC and ULB), eight national survey consultants hired by FAO (two in Sudan and one in all other countries) and the veterinary services and veterinary diagnostic laboratories of each country. The EPIAAF survey protocol is fully described in the report entitled "Report of the protocol for epidemiological surveys LoA PR 37212 between FAO and CIRAD" published in December 2007. Shortly, descriptive studies were conducted to collect standardised information on HPAI outbreaks and analytic studies were conducted to compare risk factor information for outbreak sites and non infected sites. Activities implemented during the survey are partly described in the "EPIAAF Midterm report LoA PR 37212 between FAO and CIRAD" published in May 2008 and partly described in the present report. Briefly, field investigation missions were successfully conducted in a total of 43 sites (22 case sites, 21 control sites) located in the seven countries. They enabled to fill in 55 standardised questionnaires and to collect duplicate samples (tracheal swabs, cloacal swabs and sera) from 3 672 birds. Laboratory analysis including, RRT-PCR for the detection of AI and APMV1 virus, ELISA and/or HI tests for the detection of antibodies against type A influenza, H5 AI strains, H7 AI strains, and APMV1 virus, were performed by the FAO reference laboratory in Padova. All data collected (questionnaire data, data on risk factor at the national level collected by the NSCs, laboratory results) were s

Mots-clés : influenzavirus aviaire; épidémiologie; enquête pathologique; oiseau; volaille; animal sauvage; animal domestique; facteur de risque; variation saisonnière; facteur du milieu; burkina faso; cameroun; niger; côte d'ivoire; soudan; Égypte

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