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Rift Valley fever in Mayotte in the Indian Ocean: from surveillance to genome detection

Cetre-Sossah C., Girard S., Pedarrieu A., Favre J., Defernez C., Zeller H., Grandadam M., Caro V., Petinelli F., Bouloy M., Albina E., Cardinale E.. 2014. In : Proceedings ICAHS - 2nd International Conference on Animal Health Surveillance " Surveillance against the odds", The Havana, Cuba, 7-9 May 2014. s.l. : s.n., p. 245-247. International Conference on Animal Health Surveillance. 2, 2014-05-07/2014-05-09, La Havane (Cuba).

Rift valley fever (RVF) is a zoonotic disease which circulates in many African countries as well as in the Arabian Peninsula. Epizootics are characterized by large sweeping abortion storms and significant mortality in adult livestock (primarily sheep, goats, and cattle), with newborn animal mortality approaching 100%. In most human cases, the disease is characterized by a self-limiting febrile illness progressing to more serious complications in only 1 to 2% of infected individuals (hepatitis, encephalitis, blindness or hemorrhagic syndrome. Further to the confirmation of a first human case of RVF in 2007 in Comoros, isolation of the virus was successfully achieved on suspected human cases. These viruses are genetically closely linked to the 2006-2007 Kenyan isolates. Serological surveys for antibodies to Rift Valley fever (RVF) virus were carried out in ruminants on Mayotte following the confirmation of a first human case of RVF in Comoros in 2007. The results suggested low level circulation of RVF virus on Mayotte as early as 2004, with neither human nor animal population experiencing outbreaks of the disease.

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