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The coffee genome provides insight into the convergent evolution of caffeine biosynthesis

Denoeud F., Carretero-Paulet L., Dereeper A., Droc G., Guyot R., Pietrella M., Chunfang Zheng, Alberti A., Anthony F., Aprea G., Aury J.M., Bento P., Bernard M., Bocs S., Campa C., Cenci A., Combes M.C., Crouzillat D., Da Silva C., Daddiego L., De Bellis F., Dussert S., Garsmeur O., Gayraud T., Guignon V., Jahn K., Jamilloux V., Joët T., Labadie K., Tianying Lan, Leclercq J., Lepelley M., Leroy T., Lei-Ting Li, Librado P., Lopez L., Muñoz A., Noël B., Pallavicini A., Perrotta G., Poncet V., Pot D., Priyono, Rigoreau M., Rouard M., Rozas J., Tranchant-Dubreuil C., VanBuren R., Qiong Zhang, Andrade A.A., Argout X., Bertrand B., De Kochko A., Graziosi G., Henry R., Jayarama, Ming R., Nagai C., Rounsley S., Sankoff D., Giuliano G., Albert V.A., Wincker P., Lashermes P.. 2014. Science, 345 (6201) : p. 1181-1184.

Coffee is a valuable beverage crop due to its characteristic flavor, aroma, and the stimulating effects of caffeine. We generated a high-quality draft genome of the species Coffea canephora, which displays a conserved chromosomal gene order among asterid angiosperms. Although it shows no sign of the whole-genome triplication identified in Solanaceae species such as tomato, the genome includes several species-specific gene family expansions, among them N-methyltransferases (NMTs) involved in caffeine production, defense-related genes, and alkaloid and flavonoid enzymes involved in secondary compound synthesis. Comparative analyses of caffeine NMTs demonstrate that these genes expanded through sequential tandem duplications independently of genes from cacao and tea, suggesting that caffeine in eudicots is of polyphyletic origin. (Résumé d'auteur)

Mots-clés : theobroma cacao; camellia sinensis; solanum lycopersicum; angiosperme; Évolution; phylogénie; transférase; génome; biosynthèse; caféine; coffea; coffea canephora

Thématique : Génétique et amélioration des plantes; Physiologie et biochimie végétales; Taxonomie végétale et phyto-géographie

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