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Ehrlichia's molecular tricks to manipulate their host cells

Moumène A., Meyer D.. 2016. Microbes and Infection, 18 (3) : p. 172-179.

Ehrlichia is a large genus of obligate intracellular Gram-negative bacteria transmitted by ticks that cause several emerging infectious diseases in humans and are pathogenic on rodents, ruminants, and dogs. Ehrlichia spp. invade and replicate either in endothelial cells, white blood cells, or within midgut cells and salivary glands of their vector ticks. In this review, we discuss the insights that functional studies are providing on how this group of bacteria exploits their host by subverting host innate immunity and hijacking cellular processes. (Résumé d'auteur)

Mots-clés : rodentia; ovin; ruminant; genre humain; animal sauvage; animal domestique; effecteur moléculaire; maladie transmise par vecteur; transmission des maladies; Épidémiologie; bactériologie; relation hôte pathogène; biologie moléculaire; ehrlichia; ehrlichia ruminantium

Thématique : Maladies des animaux; Organismes nuisibles des animaux

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