Commercial agricultural inoculants are increasingly being produced and sold in the market worldwide, and are claimed to have a major impact on increasing crop productivity. The proliferation of the underperforming inoculants can thereafter be prevented, and value can be added to effective products. A recent study showed that the majority of the products contained one or several strains of contaminants and only 37% of the products could be considered as pure. Forty percent of the tested products did not contain any of the claimed strains but only contaminants and several potential human pathogens were found.Results highlight the need for better quality control systems to ensure efficacious products reach the end users. This presentation will expound where we have to put more effort for increasing the quality of the commercial effective biofertilizers if we want to significantly enhancing their adoption by farmers. Examples of projects promoting biofertilizers will be presented to illustrate the problems face in the field. We will also discuss about the new Asian-Pacific network “Common Microbial Biotechnology Platform” on soil microbiology that should play a key role in the coming years for achieving this objective in this part of the world.