Since 2000, the World Vegetable Center (WorldVeg) has been promoting vegetable grafting technologies to manage soil-borne diseases (e.g., bacterial wilt) and abiotic stresses (e.g., waterlogging) in South-East Asia (Vietnam, Philippines, Indonesia, Cambodia and Lao PDR), South Asia (India, Bangladesh, Sri Lanka, Nepal and Bhutan), Oceania (Solomon Islands and Fiji), East Africa (Tanzania), West Africa (Mali and Burkina Faso), Central Asia (Uzbekistan, Armenia and Tajikistan), and Central America (Honduras and Belize). For sustainable vegetable production in developing countries, efforts are being focused on low cost-effective and simplified grafting technologies, i.e., low-cost healing chambers and grafting tubes as well as open-pollinated rootstock cultivars or those developed from wild species. Vegetable grafting has been introduced in existing value chains by training nursery operators and farm women as skill development. Moreover, grafting was also tested and promoted, along with rain shelters, for production of off-season tomatoes. The recommended rootstocks for open field production included: tomato line Hawaii 7996 (resistant to bacterial wilt and Fusarium wilt); eggplant lines EG190, EG203, and EG219 (resistant to bacterial wilt, Fusarium wilt, root-knot nematode, and short-term waterlogging); and several bacterial wilt resistant bell and hot pepper cultivars. Experience in Asia showed the impact of grafting tomato onto selected eggplant rootstocks (EG195, EG203, and EG210) which enabled the production during hot-wet periods by increasing the resistance to soil-borne diseases and flooding. For instance, vegetable grafting technology was successfully practiced in Vietnam to help stabilize tomato production (81.4 t ha -1) with the benefit-cost ratio of 4.6 for grafted compared with 3.5 for non-grafted plants. Currently, the World Vegetable Center is focusing on developing multiple biotic and abiotic stress-tolerant rootstocks and interspecific lines with vigor