The collection of Cola nitida in Côte d'Ivoire was previously classified, based on isozyme markers, into three groups named A, B and C, based on isozymic differences. In this study, morphological traits and several yield components as well as genotypic and phenotypic variabilities for vigour were investigated in groups A and B. We found that group A was characterized by a low vigour and high yield components. In contrast, group B expressed high vigour and low yield components. Intergroup hybrids were more vigorous and high yielder than intragroup hybrids. The vigour of intergroup hybrids was comparable to that of half sib commercial hybrids. Value of heterosis obtained for the yield of intergroup hybrids was 350%. It was concluded, based on our findings, that reciprocal recurrent selection in Cola nitida using plant materials of groups A and B should lead to significant improvement.