Ten pregnant female camels divided into two groups received after a 2 weeks adaptation period, an oral selenium (Se) supplementation (0 and 2 mg respectively) under sodium selenite form for 6 months from the three last months of gestation up to the three first months of lactation. Feed intake was assessed daily. Blood samples and body weight were taken on a bi-weekly basis, both in dams and their camel calves after parturition. Milk was collected at birth (colostrum), then on a bi-weekly basis. The Se concentration in serum increased significantly in the supplemented group and was threefold higher than the concentration compared to the control group, respectively 305.9 ± 103.3 ng/mL and 109.3 ± 33.1 ng/mL. Blood values in camel calves were similar to those of the dams. In calves, Se values were 106.3 ± 26.5 and 273.2 ± 48.0 ng/mL in the control and treated groups respectively. The selenium concentration increased in similar proportion in milk (86.4 ± 39.1 ng/mL in the control group vs 167.1 ± 97.3 ng/mL in treated group). In the colostrum, Se concentration was higher in the both groups, but with similar difference: it was threefold higher in treated group with a mean value 302 ± 94.60 vs 108.2 ± 43.9 ng/mL. The gluthathione-peroxidase (GSH-Px) activity in dams varied between 18.1 ± 8.7 in control group and 47.5 ± 25.6 IU/g Hb in treated group but decreased after parturition in both groups. At parturition, the camel calves born from supplemented dams had GSH-Px values threefold higher than the control calves: 73.8 ± 2.9 vs 25.0 ± 3.2 IU/g Hb (P<0.001). Vitamin E did not change significantly and was on average 1.17 ± 0.72 ng/mL and 1.14 ± 0.89 ng/mL in the control and treated group respectively. The mean value for camel calves in the control group was 0.65 ± 0.49 vs 0.82 ± 1.08 ng/mL in the treated one. Significant correlations were reported between mother serum Se, camel calf serum Se, milk Se and GSH-Px both in dams and calves. The results confirm the sensitivity