The Caribbean region is considered to be at risk for zoonotic diseases because of widespread backyard breeding system, diverse disease surveillance systems, legal or illegal human and animal movements. Several zoonosis are reported including Influenza, West Nile, Rabies, Leptospirosis. The Caribbean animal health network (CaribVET) is a collaboration among veterinary services, laboratories, research institutes, and regional/international organizations to improve animal and veterinary public health in the Caribbean. Its specific objectives are to promote a regional approach for emergency preparedness and diseases control especially for emerging and zoonotic diseases, reinforce regional diagnostic capacities, and strengthen national epidemiological surveillance systems. Meetings, trainings, skills building and development of regional tools for information and data exchange are the main strategies used. The Steering Committee of CaribVET is responsible for the regional strategy while seven Working Groups organize the collaboration on specific diseases (Tick and Tick Borne Diseases, Avian Influenza, Classical Swine Fever, Salmonellosis, Rabies) or activities (Epidemiology, Laboratory quality assurance). The epidemiology working group has developed criteria for the definition of priority diseases, core surveillance databases, an evaluation of national surveillance systems and risk analysis of regional interest. It participates in the updating of a participatory website (www.caribvet.net), with information and data on surveillance systems, diagnostic laboratories, conferences, and major diseases of the region. The Working Group for avian influenza has developed a regional surveillance protocol, a diagnostic network, surveys of wild birds and on risk posed by fighting cocks trade. Research on West Nile first developed in Guadeloupe, identified risk factors which were used to implement risk based surveillances in the region. The interaction between surveillance and research