Mycoplasma mycoides subsp. mycoides (Mmm) is responsible for contagious bovine pleuropneumonia, a severe lung disease of cattle and buffaloes. Mmm belongs to the class Mollicutes, grouping wall-less bacteria that have evolved by major gene losses and are considered the smallest self-replicating organisms. Mmm cells are known to be surrounded by a galactan pseudo-capsule, which has been associated to Mmm pathogenicity. Mmm is also able to secrete free exopolysaccharides (EPS) both in vitro and in vivo. However, these EPS have not been characterized yet because of technical difficulties due to the complexity of the mycoplasma growth medium.