Numerous parasitic and infectious diseases are emerging, re-emerging or causing recurrent outbreaks in Southeast-Asia, a hot spot of both infectious disease emergence and biodiversity at threat. Here, we present ongoing results on the potential effects of global change, biodiversity and land use on the epidemiology and diversity of infectious diseases, focusing on zoonotic diseases (and more specifically rodent-borne diseases), from regional to local scales. (Texte intégral)