The climate factors have an impact on pathogens (resistance, selection, etc), hosts (biology like immunity, ecology like migration movements, etc), vectors (ecological niches, vector capacity) and epidemiological dynamics. The climate can affect the rate of transmission, the way in which pathogens are dispersed, contact networks between individuals and between different species, community structures. Livestock farming methods, or biodiversity and its ambivalent role in disease emergence are also depending of climate factors. The diseases most sensitive to climate factors are parasitic diseases with external life-cycle, vector-borne diseases and infectious diseases passed on by water or micro-mammals including bats. Most of them are zoonosis. For a zoonosis like Ebola, several potential drivers are suspected to connect climate change to ecosystems, virus transmission to Human and heath care policies: 1. Ecology and behaviour of the bat species suspected to be Ebola virus reservoir could be affected by climate change: population density, migration, habitat utilisation, reproduction, feeding behaviour, and nature or intensity of inter-specific contacts. All those parameters would have an impact on the ecology of the Ebola virus. Therefore, researches for understanding the mechanisms of virus maintenance, circulation and transmission and for identifying reservoir and bridge species need to address the correlations between Ebola foci and its environmental factors, including climatic factors. 2. Human contamination by Ebola virus can occur through close or direct contact while hunting or through eating meat from wildlife. Climate changes can for one side, favour contact between wildlife and humans by impacting the natural habitats of the reservoir species and by influencing their movements. For other side, climate evolution may also exacerbate food insecurity, which can in turn modify human behaviour, particularly by prompting people to look for alternative food sources,