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Low seroprevalence of hepatitis E on Reunion island

Gérardin P., Porphyre V., Tsatoromila A., Cuissard L., Becquart J.P., Boussaid K., Bertolotti A., Naze F., Picot S., Filleul L., Tortosa P., Jaubert J., Guernier V., Pascalis H.. 2019. One Health, 8 : 5 p..

Objective: Hepatitis E virus (HEV) has been scarcely investigated in the Indian Ocean. Following a nationwide serosurvey among blood donors, we conducted a population-based serosurvey to assess the magnitude of HEV exposure on Reunion Island. Methods: Four hundred and sixty-six archived frozen human sera from the 2009 CoPanFlu-RUN cohort were analysed using the Wantai HEV IgG enzyme immunoassay. HEV seropositivity was defined as an IgG titre ?5 UI/ml. Raw and weighted seroprevalences were assessed to account for the discrepancy between the CoPanFlu-RUN subset and the general community. Prevalence proportion ratios (PPR) were measured using log-binomial models. Results: The raw and the weighted seroprevalences of HEV were 9.01% (95% CI 6.41¿11.61) and 6.73% (95% CI 4.47¿8.98), respectively. The presence of HEV IgG antibodies was associated with increasing age (P?

Mots-clés : population humaine; immunodiagnostic; porcin; zoonose; réunion

Thématique : Maladies des animaux; Elevage - Considérations générales

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