Mechanical properties of the ethmoid bone are not well understood due to its complex geometry (referred as a 'labyrinth'), and its deep location in the skull base. However, it is of particular interest for surgeons to appraise the force range they can apply during endoscopic procedures and know what kind of haptic feedback should be produced by a simulation device in order to be realistic for trainees (Favier et al. Citation2019). Ethmoid bone lamellae have a mainly cortical structure (Berger et al. Citation2013) which has no equivalent in the human body. The aim of this study was to describe a protocol of in-situ tensile test under microtomography (micro-CT) to characterize ethmoid bone behavior.