The main objective of cocoa genetic improvement is the selection of new clones or hybrid varieties. Field trials are therefore necessary to test these different clones or hybrid families. The families tested may represent independent crosses between clones (single pair crossing plan) or related to each other through specific crossing schemes (hierarchical, factorial or North Carolina II, diallel crossing scheme). If early screening is possible, particularly for the selection of resistant material, experimental designs are needed in the nursery or the laboratory. This involves determining designs that are statistically effective and compatible with the use of inoculation and measurement techniques on the planting material in question.