The purpose of this study was to determine the effects of road transportation under heat conditions on some haematological [Ht (haematocrit), blood cells count and EOF (erythrocytes osmotic fragility)] and physiological [Tr (rectal temperature), HR (heart) and RR (respiratory rates), and circulating levels of Cor (cortisol), Glu (glucose) and minerals] parameters in Moroccan dromedary camels. The animals were subjected to road transportation stressor for 2 h by truck during the hot-dry season. Blood samples were collected before loading and transport, and at the end of transport. Transportation induced a significant increase (P < 0.05) of erythrocytes count, Ht, EOF, Tr, HR and RR by comparison to values observed before transportation. The same stress conditions induced a significant increase (P < 0.05) of plasma Cor (ng/mL) and blood Glu (mM) (220 ± 30 vs. 137 ± 20, 9.7 ± 1.2 vs. 6.4 ± 1.1 respectively) and a significant decrease (P < 0.05) of plasma magnesium (mM) (0.5 ± 0.1 vs. 0.9 ± 0.1) comparatively to pre-transportation values. These results indicate that road transportation associated to heat may be considered as a potent stressor which is able to induce several cellular alterations in camels. Further studies of an eventual protective role of vitamin C against haemolysis induced by transportation stress in camel are needed.