Nuclear magnetic resonance imaging (MRI) has became an unavoidable medical tool in spite of its poor sensitivity. This fact motivates the efforts to enhance the nuclear magnetic resonance (NMR) probe performance. Thus, the nuclear spin excitation and detection, classically performed using radio-frequency coils, are required to be highly sensitive and homogeneous. The space harmonics suppression (SHS) method, already demonstrated to construct coil producing homogenous static magnetic field, is used in this work to design radio-frequency coils. The SHS method is used to determine the distribution of the electrical conductive wires which are organized in a saddle-coil-like configuration. The theoretical study of these SHS coils allows one to expect an enhancement of the signal-to-noise ratio with respect to saddle coil. Coils prototypes were constructed and tested to measure 1H NMR signal at a low magnetic field (8¿mT) and perform MRI acquired at a high magnetic field (3¿T). The signal-to-noise ratios of these SHS coils are compared to the one of saddle coil and birdcage (in the 3¿T case) of the same size under the same pulse sequence conditions demonstrating the performance enhancement allowed by the SHS coils.