Context: Cover crops in intercropping systems have a high potential to manage weeds in tropical agroecosystems as an herbicide alternative. However, it still needs to be better investigated in sugarcane cropping systems. Objective: This study assesses the weed control ability of cover crops in sugarcane intercropping systems depending on crop management and climate in tropical conditions. Methods: This study was based on a set of eight experiments, including ten cover crop species, performed from 2012 to 2021 in three areas in Reunion Island (France) and comparing three inter-row management treatments: i) chemical weed control, ii) cover crops sown in the inter-row, and iii) low weed control. Mean weed and cover crop ground cover were measured during the entire crop cycle, and the complementary weed management practices (herbicide, manual weeding) were also recorded. Sugarcane yield and crop management were evaluated to assess the economic impact of a change in practice. Results: Mean weed ground cover was reduced by 51 % in the cover crop and chemical treatments compared to low control. Additionally, the cover crop treatment had an herbicide treatment frequency index lower by 37 % compared to chemical treatment but a higher number of manual weedings. In all treatments, weed cover increased with rainfall and temperature. In the cover crop treatment, a structural equation modeling approach allowed us to highlight the influence of cover crop (sowing date and species) and sugarcane management (crop cycle - plant or ratoon crop) on weed cover. Weed cover decreased with an increase in cover crop ground cover, which was higher for the early sowing date. Additionally, weed cover was lower in ratoon crops than plant crops but increased over time since intercropping was implemented. Finally, sugarcane yield was lower by 6 % in cover crop treatment compared to chemical treatment. The change in operating costs and revenues between these crop management induced a decrease in pr