Three related fungi cause similar leaf diseases of banana and form the sigatoka leaf spot complex: Pseudocercospora fijiensis, P. musae et P. eumusae. The more aggressive species P. fijiensis has been recently spread throughout the world leading to a massive systematic use of fungicides in most countries, especially in industrial export plantations. Research work has been conducted to limit the use of fungicides. The development of forecasting strategies and cultural practices (such as necrotic deleafing) first allowed to reduce significantly the number of applications. Other studies have been recently conducted at landscape or farm scale to quantify the effects on epidemics of hedgerows or association with other crops. In parallel, genetic improvement programs are being conducted to create new resistant varieties. However, as for fungicides, it has been shown that pathogen populations can adapt and breakdown or erode banana resistances after 5 years of monoculture. A more durable deployment strategy would be to combine resistances with antagonistic interactions in order to constrain and limit the adaptation of pathogen populations. Studies on populations pathogen adaptation and host-pathogen interactions are thus underway. Finally, a generic model has being adapted to P. fijiensis to test the efficiency and durability of various resistance deployment strategies. The last results obtained from all these studies will be presented.