Large-scale forest restoration is vital for delivering a broad array of ecosystem services benefits to society. However, it is often perceived as an economically noncompetitive land use choice. Integrating economic opportunities into restoration aligns socioeconomic and environmental goals, reducing conflicts between forest production and conservation-oriented management decisions. Supply chains focusing on high-value goods can enhance the reach of forest restoration efforts and unite ecological and economic benefits in a multifunctional manner. The bioeconomy has emerged as a potential but critical driver for attracting investments in restoration. We outline the challenges and solutions to reconcile forest restoration and bioeconomy, specifically about (i) native timber production, (ii) non-timber forest products, (iii) biotechnological products, and (iv) intangible ecosystem services. This requires collaborative and multidisciplinary efforts to improve investment in large-scale projects. The intricacies of these issues intersect with research development, market dynamics, legal frame- works, and regulatory paradigms, underscoring the necessity for nuanced and tailored public policy interventions. These integrated approaches should enable tropical countries to lead the global forest-based economy and usher in a new era of forest restoration.