Highly pathogenic avian influenza (HPAI) and Newcastle disease (ND) are major threats to poultry production, both leading to production losses. HPAI infections in endemic and epizootic countries lead to exportation bans and thus to large economic impacts for all exporting poultry production networks. Additionally to surveillance and biosecurity measures, vaccination can be a tool for the control of HPAI and ND. While vaccination against ND is allowed in many countries, vaccination against avian influenza (AI) is still limited to few countries where the disease is endemic. Nonetheless, the devastating epidemiological situation faced since 2017 across the world has generated a lot of debates on the usage of vaccination and its potential strategies in an increased number of countries. The EVACS® tool (Evaluation of VACcination Strategies) has been developed initially to compare vaccination strategies against AI but it has since been also applied on ND. Initial applications were conducted to compare vaccination strategies using vaccines applied at the hatchery level versus vaccines applied at the farm level. New applications looked at other types of vaccination strategies, for example strategies applied on different geographic areas. The objective of this work was to compare different vaccination strategies against AI or ND between countries with various epidemiological context (enzootic and epizootic), types of vaccination (vaccine application based, geographically based) and production context (indoor or free-range, large or small farms, species produced, etc.). We analysed applications of the EVACS tool conducted between 2015 and 2022 in several countries all around the word: Egypt, Bangladesh, Indonesia, Vietnam, Tunisia and France. EVACS is a simulation tool developed in R® which allows to: model the animal production network using a social network analysis method; identify and characterise different vaccination strategies; evaluate vaccination performances using a