Bioactive peptides resulting from the hydrolysis of proteins in Chenopodium quinoa Willd. play significant roles in the body as they exhibit a range of biological functions relevant to human health. Enzymatic hydrolysis has been identified as a sustainable and efficient method for bioactive peptide extraction, minimizing environmental impact and maximizing yield. The challenge was to review and compare methodologies for obtaining peptides from protein concentrates and hydrolysates with antioxidant capabilities. Peptides and amino acids with functional properties can be used in the food and pharmaceutical industries, demonstrating significant biological activity (e.g., antioxidant and anti-inflammatory). This highlights Chenopodium quinoa as a valuable source of bioactives, though further in silico and in vivo studies are necessary to fully characterize and validate their potential.