Salmonella enterica serotype typhi with nonclassical quinolone resistance phenotype
Accou-Demartin M., Gaborieau V., Song Y., Roumagnac P., Marchou B., Achtman M., Weill F.X.. 2011. Emerging Infectious Diseases, 17 (6) : p. 1091-1094.
We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure.
Mots-clés : salmonella; sérotype; résistance aux antibiotiques; antibiotique; typhoïde; france; royaume-uni de grande-bretagne et d'irlande du nord; asie; salmonella enterica
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Agents Cirad, auteurs de cette publication :
- Roumagnac Philippe — Bios / UMR PHIM