Data driven science requires manipulating large datasets coming from various data sources through complex workflows based on a variety of models and languages. With the increasing number of big data sources and models developed by different groups, it is hard to relate models and data and use them in unanticipated ways for specific data analysis. Current solutions are typically ad-hoc, specialized for particular data, models and workflow systems. In this paper, we focus on data driven life science and propose an open service-based architecture, Life Science Workflow Services (LifeSWS), which provides data analysis workflow services for life sciences. We illustrate our motivations and rationale for the architecture with real use cases from life science.